February 2025 Research Roundtable: Inflammation with Dr. Alexandre Amato

“We can’t keep throwing gasoline on the fire,” emphasized Dr. Alexandre Amato during a riveting one-on-one conversation with Dr. Karen Herbst at the February Research Roundtable.

The fire Dr. Amato speaks of? Inflammation.

Everyone has inflammation, but lipedema fuels it differently, and Dr. Amato’s message underscored the importance of patients determining what triggers exacerbate the condition. The most common triggers – food sensitivities and leaky gut – were discussed, along with others that should be investigated: hormones, varicose veins, lack of sleep, trauma and stress, exercise (too much or not enough), and obesity.

His position is that patients receive better outcomes addressing inflammation and lipedema through conservative measures rather than surgery; less than 10% of his patients opt for surgery. In his view, lipedema fat actually protects the body from developing worse conditions. He believes that removing lipedema eliminates the protection and opines that “What happens next?” hasn’t been adequately studied. The need for functional testing, the debate over diet, GLP-1 medications, and much more made for a provocative and stimulating hour of conversation.

This Roundtable was originally recorded live on February 3, 2025, and has been edited for time. The views and opinions expressed in this program are those of the speakers and do not necessarily reflect the opinions or positions of Lympha Press. The content is for educational purposes only.

Watch more Roundtables from our Lympha Press Research Roundtables playlist on YouTube.